How to integrate Replicate MCP with Autogen

This guide walks you through connecting Replicate to AutoGen using the Composio tool router. By the end, you'll have a working Replicate agent that can run stable diffusion to generate an image, list all your uploaded files on replicate, get readme documentation for a model through natural language commands. This guide will help you understand how to give your AutoGen agent real control over a Replicate account through Composio's Replicate MCP server. Before we dive in, let's take a quick look at the key ideas and tools involved.

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Introduction

This guide will help you understand how to give your AutoGen agent real control over a Replicate account through Composio's Replicate MCP server.

Before we dive in, let's take a quick look at the key ideas and tools involved.

Also integrate Replicate with

ChatGPT OpenAI Agents SDK Claude Agent SDK Claude Code Claude Cowork Codex OpenCode Cursor VS Code OpenClaw Hermes CLI Google ADK LangChain Vercel AI SDK Mastra AI LlamaIndex CrewAI

TL;DR

Here's what you'll learn:

Get and set up your OpenAI and Composio API keys
Install the required dependencies for Autogen and Composio
Initialize Composio and create a Tool Router session for Replicate
Wire that MCP URL into Autogen using McpWorkbench and StreamableHttpServerParams
Configure an Autogen AssistantAgent that can call Replicate tools
Run a live chat loop where you ask the agent to perform Replicate operations

What is AutoGen?

Autogen is a framework for building multi-agent conversational AI systems from Microsoft. It enables you to create agents that can collaborate, use tools, and maintain complex workflows.

Key features include:

Multi-Agent Systems: Build collaborative agent workflows
MCP Workbench: Native support for Model Context Protocol tools
Streaming HTTP: Connect to external services through streamable HTTP
AssistantAgent: Pre-built agent class for tool-using assistants

What is the Replicate MCP server, and what's possible with it?

The Replicate MCP server is an implementation of the Model Context Protocol that connects your AI agent and assistants like Claude, Cursor, etc directly to your Replicate account. It provides structured and secure access to your Replicate resources, so your agent can perform actions like running AI model predictions, managing files, browsing model collections, and retrieving model documentation on your behalf.

Run and manage AI model predictions: Easily instruct your agent to create, monitor, and manage predictions on any deployed Replicate model using custom input parameters.
Browse and discover model collections: Ask your agent to fetch and list available model collections or retrieve example predictions to explore what’s possible on Replicate.
Upload and organize files: Let your agent upload new files, list all stored files, or inspect file details to streamline your model workflows.
Access model metadata and documentation: Retrieve full model details, schemas, and markdown README docs for any model to help you choose and utilize the right model for your tasks.

What is the Composio tool router, and how does it fit here?

What is Composio SDK?

Composio's Composio SDK helps agents find the right tools for a task at runtime. You can plug in multiple toolkits (like Gmail, HubSpot, and GitHub), and the agent will identify the relevant app and action to complete multi-step workflows. This can reduce token usage and improve the reliability of tool calls. Read more here: Getting started with Composio SDK

The tool router generates a secure MCP URL that your agents can access to perform actions.

How the Composio SDK works

The Composio SDK follows a three-phase workflow:

Discovery: Searches for tools matching your task and returns relevant toolkits with their details.
Authentication: Checks for active connections. If missing, creates an auth config and returns a connection URL via Auth Link.
Execution: Executes the action using the authenticated connection.

Step-by-step Guide

Step by step08 STEPS

Prerequisites

You will need:

A Composio API key
An OpenAI API key (used by Autogen's OpenAIChatCompletionClient)
A Replicate account you can connect to Composio
Some basic familiarity with Autogen and Python async

Getting API Keys for OpenAI and Composio

OpenAI API Key

Go to the OpenAI dashboard and create an API key. You'll need credits to use the models, or you can connect to another model provider.
Keep the API key safe.

Composio API Key

Log in to the Composio dashboard.
Navigate to your API settings and generate a new API key.
Store this key securely as you'll need it for authentication.

Install dependencies

bash

pip install composio python-dotenv
pip install autogen-agentchat autogen-ext-openai autogen-ext-tools

Install Composio, Autogen extensions, and dotenv.

What's happening:

composio connects your agent to Replicate via MCP
autogen-agentchat provides the AssistantAgent class
autogen-ext-openai provides the OpenAI model client
autogen-ext-tools provides MCP workbench support

Set up environment variables

bash

COMPOSIO_API_KEY=your-composio-api-key
OPENAI_API_KEY=your-openai-api-key
USER_ID=your-user-identifier@example.com

Create a .env file in your project folder.

What's happening:

COMPOSIO_API_KEY is required to talk to Composio
OPENAI_API_KEY is used by Autogen's OpenAI client
USER_ID is how Composio identifies which user's Replicate connections to use

Import dependencies and create Tool Router session

python

import asyncio
import os
from dotenv import load_dotenv
from composio import Composio

from autogen_agentchat.agents import AssistantAgent
from autogen_ext.models.openai import OpenAIChatCompletionClient
from autogen_ext.tools.mcp import McpWorkbench, StreamableHttpServerParams

load_dotenv()

async def main():
    # Initialize Composio and create a Replicate session
    composio = Composio(api_key=os.getenv("COMPOSIO_API_KEY"))
    session = composio.create(
        user_id=os.getenv("USER_ID"),
        toolkits=["replicate"]
    )
    url = session.mcp.url

What's happening:

load_dotenv() reads your .env file
Composio(api_key=...) initializes the SDK
create(...) creates a Tool Router session that exposes Replicate tools
session.mcp.url is the MCP endpoint that Autogen will connect to

Configure MCP parameters for Autogen

python

# Configure MCP server parameters for Streamable HTTP
server_params = StreamableHttpServerParams(
    url=url,
    timeout=30.0,
    sse_read_timeout=300.0,
    terminate_on_close=True,
    headers={"x-api-key": os.getenv("COMPOSIO_API_KEY")}
)

Autogen expects parameters describing how to talk to the MCP server. That is what StreamableHttpServerParams is for.

What's happening:

url points to the Tool Router MCP endpoint from Composio
timeout is the HTTP timeout for requests
sse_read_timeout controls how long to wait when streaming responses
terminate_on_close=True cleans up the MCP server process when the workbench is closed

Create the model client and agent

python

# Create model client
model_client = OpenAIChatCompletionClient(
    model="gpt-5",
    api_key=os.getenv("OPENAI_API_KEY")
)

# Use McpWorkbench as context manager
async with McpWorkbench(server_params) as workbench:
    # Create Replicate assistant agent with MCP tools
    agent = AssistantAgent(
        name="replicate_assistant",
        description="An AI assistant that helps with Replicate operations.",
        model_client=model_client,
        workbench=workbench,
        model_client_stream=True,
        max_tool_iterations=10
    )

What's happening:

OpenAIChatCompletionClient wraps the OpenAI model for Autogen
McpWorkbench connects the agent to the MCP tools
AssistantAgent is configured with the Replicate tools from the workbench

Run the interactive chat loop

python

print("Chat started! Type 'exit' or 'quit' to end the conversation.\n")
print("Ask any Replicate related question or task to the agent.\n")

# Conversation loop
while True:
    user_input = input("You: ").strip()

    if user_input.lower() in ["exit", "quit", "bye"]:
        print("\nGoodbye!")
        break

    if not user_input:
        continue

    print("\nAgent is thinking...\n")

    # Run the agent with streaming
    try:
        response_text = ""
        async for message in agent.run_stream(task=user_input):
            if hasattr(message, "content") and message.content:
                response_text = message.content

        # Print the final response
        if response_text:
            print(f"Agent: {response_text}\n")
        else:
            print("Agent: I encountered an issue processing your request.\n")

    except Exception as e:
        print(f"Agent: Sorry, I encountered an error: {str(e)}\n")

What's happening:

The script prompts you in a loop with You:
Autogen passes your input to the model, which decides which Replicate tools to call via MCP
agent.run_stream(...) yields streaming messages as the agent thinks and calls tools
Typing exit, quit, or bye ends the loop

Complete Code

Here's the complete code to get you started with Replicate and AutoGen:

python

import asyncio
import os
from dotenv import load_dotenv
from composio import Composio

from autogen_agentchat.agents import AssistantAgent
from autogen_ext.models.openai import OpenAIChatCompletionClient
from autogen_ext.tools.mcp import McpWorkbench, StreamableHttpServerParams

load_dotenv()

async def main():
    # Initialize Composio and create a Replicate session
    composio = Composio(api_key=os.getenv("COMPOSIO_API_KEY"))
    session = composio.create(
        user_id=os.getenv("USER_ID"),
        toolkits=["replicate"]
    )
    url = session.mcp.url

    # Configure MCP server parameters for Streamable HTTP
    server_params = StreamableHttpServerParams(
        url=url,
        timeout=30.0,
        sse_read_timeout=300.0,
        terminate_on_close=True,
        headers={"x-api-key": os.getenv("COMPOSIO_API_KEY")}
    )

    # Create model client
    model_client = OpenAIChatCompletionClient(
        model="gpt-5",
        api_key=os.getenv("OPENAI_API_KEY")
    )

    # Use McpWorkbench as context manager
    async with McpWorkbench(server_params) as workbench:
        # Create Replicate assistant agent with MCP tools
        agent = AssistantAgent(
            name="replicate_assistant",
            description="An AI assistant that helps with Replicate operations.",
            model_client=model_client,
            workbench=workbench,
            model_client_stream=True,
            max_tool_iterations=10
        )

        print("Chat started! Type 'exit' or 'quit' to end the conversation.\n")
        print("Ask any Replicate related question or task to the agent.\n")

        # Conversation loop
        while True:
            user_input = input("You: ").strip()

            if user_input.lower() in ['exit', 'quit', 'bye']:
                print("\nGoodbye!")
                break

            if not user_input:
                continue

            print("\nAgent is thinking...\n")

            # Run the agent with streaming
            try:
                response_text = ""
                async for message in agent.run_stream(task=user_input):
                    if hasattr(message, 'content') and message.content:
                        response_text = message.content

                # Print the final response
                if response_text:
                    print(f"Agent: {response_text}\n")
                else:
                    print("Agent: I encountered an issue processing your request.\n")

            except Exception as e:
                print(f"Agent: Sorry, I encountered an error: {str(e)}\n")

if __name__ == "__main__":
    asyncio.run(main())

Conclusion

You now have an Autogen assistant wired into Replicate through Composio's Tool Router and MCP. From here you can:

Add more toolkits to the toolkits list, for example notion or hubspot
Refine the agent description to point it at specific workflows
Wrap this script behind a UI, Slack bot, or internal tool

Once the pattern is clear for Replicate, you can reuse the same structure for other MCP-enabled apps with minimal code changes.

TOOLS

Supported Tools

Every Replicate action and event your agent gets out of the box.

Get Account Information

Tool to get authenticated account information.

Cancel Prediction

Tool to cancel a prediction that is still running.

Get model collection

Tool to get a specific collection of models by its slug.

List model collections

Tool to list all collections of models.

Create Model

Tool to create a new Replicate model with specified owner, name, visibility, and hardware.

Create Prediction

Tool to create a prediction for a Replicate Deployment.

Create Deployment

Tool to create a new deployment with specified model, version, hardware, and scaling parameters.

Delete Deployment

Tool to delete a deployment from your account.

Get Deployment Details

Tool to get deployment details by owner and name.

List deployments

Tool to list all deployments associated with the account.

Create File

Tool to create or upload a file to Replicate.

Delete File

Tool to delete a file by its ID.

Get File Details

Tool to get details of a file by its ID.

List Files

Tool to retrieve a paginated list of uploaded files.

Get Prediction

Tool to get the status and output of a prediction by its ID.

List Available Hardware

Tool to list available hardware SKUs for models and deployments.

List model examples

Tool to list example predictions for a specific model.

Get Model Details

Tool to get details of a specific model by owner and name.

List Public Models

Tool to list public models with pagination and sorting.

Create Model Prediction

Tool to create a prediction using an official Replicate model.

Get Model README

Tool to get the README content for a model in Markdown format.

Get Model Version

Tool to get a specific version of a model.

List Model Versions

Tool to list all versions of a specific model.

Create Prediction

Tool to create a prediction to run a model by version ID.

List All Predictions

Tool to list all predictions for the authenticated user or organization with pagination.

Search Models and Collections

Tool to search for models, collections, and docs using text queries (beta).

Cancel Training

Tool to cancel an ongoing training operation in Replicate.

Create Training Job

Tool to create a training job for a specific model version.

List Training Jobs

Tool to list all training jobs for the authenticated user or organization with pagination.

Update Model Metadata

Tool to update metadata for a model including description, URLs, and README.

Get Webhook Signing Secret

Tool to get the signing secret for the default webhook.

FRAMEWORKS

How to build Replicate MCP Agent with another framework

ChatGPT

Use Replicate MCP with ChatGPT

OpenAI Agents SDK

Use Replicate MCP with OpenAI Agents SDK

Claude Agent SDK

Use Replicate MCP with Claude Agent SDK

Claude Code

Use Replicate MCP with Claude Code

Claude Cowork

Use Replicate MCP with Claude Cowork

Codex

Use Replicate MCP with Codex

Cursor

Use Replicate MCP with Cursor

OpenClaw

Use Replicate MCP with OpenClaw

Hermes

Use Replicate MCP with Hermes

CLI

Use Replicate MCP with CLI

Google ADK

Use Replicate MCP with Google ADK

LangChain

Use Replicate MCP with LangChain

Vercel AI SDK

Use Replicate MCP with Vercel AI SDK

Mastra AI

Use Replicate MCP with Mastra AI

LlamaIndex

Use Replicate MCP with LlamaIndex

CrewAI

Use Replicate MCP with CrewAI

OpenCode

Use Replicate MCP with OpenCode

VS Code

Use Replicate MCP with VS Code

MORE TOOLKITS

Explore Other Toolkits

Toolkit marketplace

Composio

No Auth

Composio is an integration platform that connects AI agents with hundreds of business tools. It streamlines authentication and lets you trigger actions across services—no custom code needed.

Composio search

No Auth

Composio search is a unified web search toolkit spanning travel, e-commerce, news, financial markets, images, and more. It lets you and your apps tap into up-to-date web data from a single, easy-to-integrate service.

Perplexityai

Api Key

Perplexityai delivers natural, conversational AI models for generating human-like text. Instantly get context-aware, high-quality responses for chat, search, or complex workflows.

Browser tool

No Auth

Browser tool is a virtual browser integration that lets AI agents interact with the web programmatically. It enables automated browsing, scraping, and action-taking from any AI workflow.

FAQ

Frequently asked questions

With a standalone Replicate MCP server, the agents and LLMs can only access a fixed set of Replicate tools tied to that server. However, with the Composio Tool Router, agents can dynamically load tools from Replicate and many other apps based on the task at hand, all through a single MCP endpoint.

Yes, you can. Autogen fully supports MCP integration. You get structured tool calling, message history handling, and model orchestration while Tool Router takes care of discovering and serving the right Replicate tools.

Yes, absolutely. You can configure which Replicate scopes and actions are allowed when connecting your account to Composio. You can also bring your own OAuth credentials or API configuration so you keep full control over what the agent can do.

All sensitive data such as tokens, keys, and configuration is fully encrypted at rest and in transit. Composio is SOC 2 Type 2 compliant and follows strict security practices so your Replicate data and credentials are handled as safely as possible.

Start with Replicate.It takes 30 seconds.

Managed auth, hosted MCP servers, and every Replicate tool your agent needs.Free to start.

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Customer stories

Teams ship real agents on Composio

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Karan skipped his own birthday party to fix our critical issue. It was 10pm and he diverted his Waymo to help us instead. This really sets the bar — it shows the commitment you need when users rely on your software.

Harsha Gaddipati

Co-founder, Slashy

A lot of students tell us that the moment their connected tools start talking to each other inside Opennote feels almost magical. The agent just knows them, and it's immensely helped keep new users on the platform.

Abhi Arya

Co-founder, Opennote

We chose Composio over Pipedream because it delivered depth where it mattered — niche tools and tricky edge cases other platforms simply ignored. That gave us confidence to scale without compromising.

Nirman Dave

CEO, Zams

As a solo builder, shipping fast is life or death. The only way I can outcompete incumbents is by outmanoeuvring them. Getting bogged down managing agent auth would have been a death sentence.

Ryan Yu

Founder, Extra Thursday

Before Composio, adding tool integrations was slow and resource-intensive. Each one could take weeks of engineering time, and maintaining them meant constantly keeping up with API changes.

Tomisin Jenrola

Founder & CEO, SwarmZero

With hands-on help from their founder, we integrated Gmail and Google Drive in just 30 minutes. This level of personal support and commitment is exactly what startups should strive for.

Jerome Leclanche

Co-Founder, Ingram Technologies

How to integrate Replicate MCP with Autogen

Connect Replicate without auth hassles

Introduction

Also integrate Replicate with

TL;DR

What is AutoGen?

What is the Replicate MCP server, and what's possible with it?

What is the Composio tool router, and how does it fit here?

What is Composio SDK?

How the Composio SDK works

Step-by-step Guide

Prerequisites

Getting API Keys for OpenAI and Composio

Install dependencies

Set up environment variables

Import dependencies and create Tool Router session

Configure MCP parameters for Autogen

Create the model client and agent

Run the interactive chat loop

Complete Code

Conclusion

Supported Tools

How to build Replicate MCP Agent with another framework

ChatGPT

OpenAI Agents SDK

Claude Agent SDK

Claude Code

Claude Cowork

Codex

Cursor

OpenClaw

Hermes

CLI

Google ADK

LangChain

Vercel AI SDK

Mastra AI

LlamaIndex

CrewAI

OpenCode

VS Code

Explore Other Toolkits

Composio

Composio search

Perplexityai

Browser tool

Frequently asked questions

What are the differences in Tool Router MCP and Replicate MCP?+

Can I use Tool Router MCP with Autogen?+

Can I manage the permissions and scopes for Replicate while using Tool Router?+

How safe is my data with Composio Tool Router?+

Start with Replicate.It takes 30 seconds.

Teams ship real agents on Composio